Topic: Update on Lisa
I have not posted for quite some time, so I wanted to provide a quick update on my wife Lisa. Lisa was diagnosed with stage four ICC in May of last year with a very large mass (15cm) and several smaller masses in both lobes of her liver. She also had positive retroperitoneal lymph nodes. After consultations with our local team as well as second opinions at Mayo and Sloan Kettering, we learned that she was inoperable due to the tumor size, location, and extrahepatic spread.
Her tumors all grew slightly after 6 cycles of GEM/CIS and her CA19-9 continued to rise. Needless to say, we were very concerned at this point. The chemotherapy was switched to folfirinox, and fortunately, Lisa had a great response after 8 cycles of this second line treatment. Against all odds, Lisa became operable and was able to have a resection surgery (trisegmentectomy, along with several other procedures) approximately one month ago.
The surgery was successful and all visible cancer was removed; however, the surgeon was not able to achieve negative margins along the hepatic vein. Lisa will undergo six weeks of chemo-radiation (IMRT with Xeloda) starting in a few weeks to treat the R1 margin and potentially the lymph nodes as well. Her CA19-9 from last week was 13 after a high of 1,880. Needless to say, we are ecstatic over such a positive result.
As with all patients on this message board, the experience this past eight months has definitely been a roller coaster. The folfirinox treatments were very rough on Lisa and she is still experiencing significant neuropathy which we hope will end soon. The recovery from her surgery has also been very challenging, and she certainly is not looking forward to the radiation treatments. However, we feel very blessed overall given the initial prognosis.
We have made numerous connections through this message board and Lisa is extremely thankful to all of those who have provided support over these last several months. I hope to become a more frequent contributor to this site and will post additional updates going forward.