Lorna....Gemzar (gemcitabine) had been a standard of treatment. The ABC-1 and ABC-2 clinical trial (UK) compared to gemcitabine alone, the chemotherapy combination of cisplatin and gemcitabine and data showed improved overall survival of patients with locally advanced or metastatic cholangiocarcinoma. This is data reflects results of patients with detectable disease however; given the fact that we don't have any other large scale studies proven otherwise, physicians like to use this reasoning for adjuvant therapy as well. To this date we still don't have prove whether adjuvant therapy is beneficial, but we are awaiting results of some studies within this year.
THIS INFORMATION IS NOT INTENDED NOR IMPLIED TO BE A SUBSTITUTE FOR PROFESSIONAL MEDICAL ADVICE. YOU SHOULD ALWAYS SEEK THE ADVICE OF YOUR PHYSICIAN OR OTHER QUALIFIED HEALTH CARE PROVIDER