Topic: Stacie and others: a review of the treatment options
I have a CT scan this week and I'm seeing my oncologist next week and I'm trying to prepare a list of treatment options to discuss (in case my Gem-Carbo chemo is not working). At the risk of going over what for many of you is "old ground" I'd be most grateful for your comments on the following (and anything I've missed). I've read and learned a lot on this website, and done some of my own research, what I need is to summarise the situation.
Are there any early results from clinical trials, or maybe just individual case reports, regarding the effectiveness of the drug in delaying disease progression and/or extending survival times in respect of CC or pancreatic cancer, for:
Approved in the US for colorectal cancer and apparently Caroline will get to receive it for CC. I'm not aware of any trials for CC or pancreatic. I believe the UK's Royal Marsden hospital are conducting a trial of an alternative angeogenic drug, AZ2171, which they described to me as a "2nd generation avastin".
Not sure whether this is "mainstream". A lot of the reports about Davanat seem to come from the developer "Pro-Pharmaceuticals" and of course they have a commercial interest to promote.
There are phase-3 clinical trials under way but as far as I know these are "blind" trials so I guess results won't be available until after the trials are completed. Not sure whether any stage-2 trials results are available.
The only positive reports I've seen relate to kidney cancer.
A chemo drug for colorectal and breast cancer. From what I read it's no more effective that 5FU, just more convenient (it is oral) and less side effects. Caroline reported that she tried Xeloda without any success.
The subject of much research worldwide and possibly the definitive cancer treatment of the future. I have seen a recently published "report of a case" from Japan where a woman with CC was treated with surgery and post-op immunotherapy and, despite lymph node metastasis, she is still alive 3.5 years later. But I have not seen any reports of wider use of this form of treatment.
Again I'm looking for real evidence of effectiveness, which I recognise will probably not exist.
I recently met an oncologist in UK (a specialist in cancer vaccine research) who recommended the following which he said has been shown to shrink tumours:
Green Tea extract
Bromelain (an enzyme derived from pinapples)
Asprin (yes asprin!)
In addition have seen references to:
Active Hexose Correlated Compound (AHCC) - derived from mushrooms and the subject of an informal trial in Japan.
Fermented wheat germ extract - I've just seen Stacie's post on this, and read a couple of the references, it sounds very promising.